1、

Study on the diabetic model induced by streptozocin in Wistar rats

链脲佐菌素致大鼠高血糖模型的实验研究

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MATERIALS: This experiment was conducted at the Department of Histology& Embryology, School of Basic Medical Science, Jilin University from October 2004 to October 2005. The rat amniotic epithelial tissue was mechanically peeled from an embryonic 12 to 14 days Wistar rats.

材料:实验于2004-10/2005-10在吉林大学基础医学院组织与胚胎学教研室完成。选取清洁级孕12~14d的Wistar大鼠1只,将分离出的羊膜上皮细胞用于实验。

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Participants were 10 purebred Wistar rats in clean grade, weighing 200-250 g, purchased from Center for Experimental Animals, Jilin University, and feeding condition was at 20-25 ℃, humidity of 60%-70%.

对象:清洁级纯种Wistar大鼠,雌雄不限,体质量200~250g,购自吉林大学实验动物中心,饲养环境温度20~25℃,湿度60%~70%。

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Studies on growth and reproduction in BB Wistar rats with spontaneous diabetes

自发性糖尿病大鼠生长发育与繁殖研究

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Methods Hyperoxaluria and CaOx crystal were produced in Wistar rats by ethylene glycol in drinking water.

方法用乙二醇诱导Wistar大鼠产生肾草酸钙结石。

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Wistar rats were divided into two groups randomly. including the control model group and the XBJ group.

将Wistar大鼠随机分为2组:①模型对照组(CON);②血必净注射液组(XBJ)。

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Methods The OEG was cultured with the olfactory bulb of Wistar neonate rats.

方法用新生Wistar大鼠嗅球做OEG培养,大量增殖并标记。

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Cell culture: The primary OEG was cultivated with the olfactory bulb of Wistar neonate rats, and then the purification was done by free serum medium.

细胞培养:新生Wistar大鼠嗅球(OB)做OEG原代培养,然后利用无血清培养基添加一些促进生长的微量物质做纯化培养,为OEG提供了合适的生长环境而大量增殖。

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Induction of pulmonary precancerous lesions by tobacco-specific NNK in Wistar rats

烟草致癌原NNK诱发大鼠肺癌前病变的实验研究

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Methods Wistar rat and Kunming mouse were used as experimental animals. Osteoporosis was induced by orally given retinoic acid ( 70 mg · kg-1 · d-1) to the rats for 14 dasy.

方法:维甲酸(70mg·Kg-1·d-1)给大鼠灌胃14d,可导致大鼠的实验性骨质疏松,然后观察药物对动物骨密度的影响;

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MATERIALS: The experiment was conducted in the Experiment Center of Stomatology Hospital, Wuhan University, from September 2003 to January 2004. Three healthy male Wistar rats of clean grade were used.

材料:实验于2003-9/2004-01在武汉大学口腔医院实验中心完成。选用清洁级健康雄性Wistar大鼠3只。

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Methods: DM rat models were established successfully by streptozocin ( STZ) injection which caused high level of blood glucose in Wistar rats.

方法:采用链脲菌素(STZ)诱发Wistar大鼠产生高血糖,建立1型糖尿病大鼠模型。

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Glucose and insulin levels in serum, androgen-binding protein ( ABP) and nuclear androgen receptor ( NAR) in testis were determined in streptozocin-induced diabetic and the control Wistar rats.

静脉注射链脲菌素复制糖尿病模型后80天,处死动物,测定血糖,血浆胰岛素浓度及睾丸雄激素结合蛋白(ABP)和细胞核雄激素受体。

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Methods Female Wistar rats were injected a low dose of streptozotocin ( 30mg/ kg) intraperitoneally followed by a high fat high fructose diet and drank 10% fructose water.

方法腹腔注射小剂量链脲霉素(streptozotocin,STZ),30mg/kg轻度损伤胰岛β细胞,造成大鼠糖耐量异常后加喂高果糖高脂肪饲料,并饮用10%果糖水,造成胰岛素抵抗。

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Methods 1. The diabetes Wistar rats were induced by intravenous administration of streptozotocin ( STZ) in a single dose of 60mg/ kg via penis dorsal vein.

【方法】1.采用链脲霉素(streptozotocin,STZ)60mg/kg尾静脉一次性注射法诱导建立Wistar大鼠Ⅰ型糖尿病模型。

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Observation on change of lipidemia and lipoprotein in wistar rats with fluorosis

慢性氟中毒大鼠血脂及载脂蛋白的变化

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Objective: To observe the morphologic changes of pituitary adrenocorticotrophic hormone ( ACTH) cells in Wistar rats at different altitudes, and clarify the mechanism of stress reaction to hypoxia in ACTH cells.

目的:观察Wistar大鼠急速进入不同海拔高度的腺垂体促肾上腺皮质激素(ACTH)细胞的形态结构变化,为探讨ACTH细胞在机体对低氧应激反应中的作用提供形态学依据。

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Methods Eighteen Wistar rats were divided into three groups: normal control group ( NCG), hepatic fibrosis group ( HFG) and hepatic cirrhosis group treated with complex pathogens ( HCG).

方法将18只Wistar大鼠分为三组:正常对照组(NCG)、复合因素致肝纤维化组(HFG)、肝硬化组(HCG)。

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The Effect of Metal Particles from a Nickel Refinery Dump on Alveolar Macrophages& Chamber Exposure of Wistar Rats

冶镍金属颗粒对泡状巨噬细胞的影响&藤鼠的室内暴露实验

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Methods Uninephrectomized male Wistar rats were used to induce diabetic models by ip Streptozocin ( 65 mg/ kg).

方法ip链脲佐菌素(65mg/kg)诱发糖尿病大鼠模型,每日ip葛根素注射液,共16周。

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